Aluminum Zirconium Tetrachlorohydrex Gly

Aluminum zirconium tetrachlorohydrex glycine

Also searched asAluminum Zirconium Tetrachlorohydrex GlycineAluminium Zirconium Tetrachlorohydrex Glyaluminum zirconium tetrachlorohydrex glycine
Role
Temporarily reduces sweat release in the treated area.
Catalog formulas
9
Type
Active
Verified
06.11.2026

What does this ingredient do in an antiperspirant?

A complex aluminum-zirconium salt stabilized with the amino acid glycine. Like other aluminum salts, it forms temporary gel plugs in the sweat ducts that clear as the skin renews itself.

Part of a system, not a label in isolation

It is found in sticks, gels and roll-ons. The FDA allows this active at up to 20% (calculated on an anhydrous basis) in non-aerosol forms only; in the EU, aluminum-zirconium complexes are likewise banned from aerosol dispensers.

Regulatory and scientific context

In the EU it is permitted only in antiperspirants: up to 20% as the anhydrous complex and up to 5.4% as zirconium, with the mandatory warning "do not apply to irritated or damaged skin". The SCCS considers aluminum compounds safe in cosmetics within the limits assessed in opinion SCCS/1662/23.

What sensitive skin should consider

Under FDA rules, the label must say not to use it on broken skin and to stop use if a rash or irritation occurs. Stinging is more likely on damp or freshly shaved skin.

Do not confuse with

It is not the same as Aluminum Chlorohydrate: the FDA allows the chlorohydrate at up to 25% and in aerosols too, while aluminum-zirconium salts are capped at 20% and limited to non-aerosol forms. It differs from Trichlorohydrex Gly and Octachlorohydrex Gly in the ratio of aluminum, zirconium and chlorine atoms set by the US Pharmacopeia (USP–NF).

Products containing Aluminum Zirconium Tetrachlorohydrex Gly

Links are based on the complete published INCI list for the exact product version.

ProductFormatRole in the formulaFull analysis
MartiDerm Driosec Intensive Roll-On 50 mlroll-onantiperspirant active ingredientOpen
Lady Speed Stick Invisible Protection 45 gstickantiperspirant active ingredientOpen
Deonica PRO-Protection antiperspirant 50 mlroll-onantiperspirant active ingredientOpen
Dove Advanced Care Sensitive stick 74 gstickantiperspirant active ingredientOpen
Degree Clinical Protection 5 in 1 stick 48 gstickantiperspirant active ingredientOpen
Degree Men Clinical Protection Sport Strength stick 48 gstickantiperspirant active ingredientOpen
Dove Men+Care Clinical Protection Clean Comfort stick 48 gstickantiperspirant active ingredientOpen
Deonica For Men Antibacterial roll-on 50 mlroll-onantiperspirant active ingredientOpen
Biotherm Deo Pure stick 48H 40 mlstickantiperspirant active ingredientOpen

Sources

The conclusions apply to the stated conditions and jurisdictions, not automatically to every concentration or product.

  1. FDA OTC Monograph M019 Supports: list of active ingredients, permitted concentration, dosage form, label warnings
  2. Regulation (EC) 1223/2009, Annex III, entry 50 Supports: permitted concentration, restrictions, label warnings
  3. SCCS/1662/23: safety of aluminum in cosmetic products Supports: safety assessment, conditions of use